ppt download Biology Diagrams The duration of the cell cycle varies from one cell type to another. Most human cells complete the cycle in about 24 hours. Fast-growing cells, like those in the lining of the intestine, may complete it in just 9 or 10 hours, while liver cells take more than a year and neuronal cells take many years. The cell cycle and cancer
The cell-cycle state of stem cells determines cell fate propensity. Cell 155 , 135-147 (2013). Article CAS PubMed PubMed Central Google Scholar
Cancer stem cells: advances in knowledge and implications for cancer ... Biology Diagrams
Cell cycle regulation depends on phase-specific transcriptions of cell cycle genes. The alterations of cell cycle genes can predispose normal cells to have a cancerous phenotype. Indeed, several mechanisms underlying the deregulation of the cell cycle have been identified in different types of cancer.
Pluripotency is also linked with cell-cycle regulation because studies in mouse ESCs (mESCs) have shown that their pluripotent status is associated with a specific cell-cycle profile characterized by a shortened G1 phase and the lack of G1 checkpoint regulation (Coronado et al., 2013; Savatier et al., 1996).In conventional cells, cyclin D1-3 are expressed in G1 phase and control the activity
The cell cycle in stem cell proliferation, pluripotency and ... Biology Diagrams
Cancer stem cells and the cell cycle: targeting the drive behind breast cancer. Cancer stem cells and the cell cycle: targeting the drive behind breast cancer Expert Rev Anticancer Ther. 2009 Mar;9(3):275-9. doi: 10.1586/14737140.9.3.275. Authors Marco A In addition to the properties of self-renewal and multipotency, cancer stem cells share the characteristics of their distinct cell cycle status with somatic stem cells. Cancer stem cells (CSCs) are maintained in a quiescent state with this characteristic conferring resistance to anticancer therapies that target dividing cells. Elucidation of
